leucine + glycerol

Leucine + glycerol is a combination used in parenteral nutrition, most notably as the product ProcalAmine. This formulation provides essential and nonessential amino acids (including leucine) alongside glycerol as a non-protein energy source. Leucine is an essential branched-chain amino acid that supports protein synthesis, muscle mass preservation, nitrogen balance, and metabolic regulation by activating the mTOR pathway. Glycerol serves as an energy substrate; it is metabolized primarily in the liver for gluconeogenesis and energy production via conversion to dihydroxyacetone phosphate. The combination aims to preserve body protein and improve nitrogen balance in patients requiring short-term parenteral nutrition who are mildly catabolic but otherwise well-nourished[1][4][6].

Brand names

ProcalAmine

Other names

amino acid and glycerin3% amino acid and 3% glycerin injection