Drug intelligence / Profile preview

levocetirizine + tranexamic acid

Development stage
Preclinical
Lead developer
UCB
Modality
Small Molecules
Administration
Oral
01

Overview

This is a combination of two medications: levocetirizine, a second-generation H1-receptor antagonist (antihistamine), and tranexamic acid, an antifibrinolytic agent. Levocetirizine works by selectively inhibiting histamine H1 receptors, preventing histamine from causing allergic symptoms. Tranexamic acid competitively inhibits the activation of plasminogen to plasmin, preventing the breakdown of blood clots and reducing bleeding. This combination has been studied for treating chronic spontaneous urticaria.

02

Targets

PLG (Plasminogen)HRH1 (Histamine H1 Receptor)

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