Drug intelligence / Profile preview

levodropropizine + pelargonium sidoides extract

Development stage
Unknown
Lead developer
PBK
Modality
Small Molecules
Administration
Oral
01

Overview

A combination of **levodropropizine**, a peripherally acting non-opioid antitussive, and **pelargonium sidoides extract**, a herbal extract with immunomodulatory and possible antimicrobial properties, primarily intended for the symptomatic treatment of **cough** and upper respiratory tract infections. Levodropropizine acts by inhibiting sensory C-fibers in the airway to suppress the cough reflex without significant central nervous system depression. Pelargonium sidoides extract is derived from the roots of the South African plant *Pelargonium sidoides* and is shown to have effects against pathogens associated with respiratory infections, and promotes immune responses. The combination is under development for enhanced therapeutic effect in respiratory infections and cough, benefiting from both antitussive and immunomodulatory actions[1][4].

Other names
levodropropizine + Pelargonium sidoides extract
02

Targets

SP (Substance P)

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