Drug intelligence / Profile preview

levonorgestrel + lactational amenorrhea method

Development stage
Unknown
Lead developer
Assiut University
Modality
Small Molecules
Administration
Oral
01

Overview

This intervention combines the Lactational Amenorrhea Method (LAM) with the advance provision of levonorgestrel emergency contraceptive pills (LNG-ECPs). LAM is a natural family planning method based on the physiological infertility caused by breastfeeding, which is effective only when specific prerequisites are met: the mother is less than six months postpartum, remains amenorrheic, and practices exclusive or near-exclusive breastfeeding. The intervention involves counseling postpartum women on LAM and providing them with a backup supply of levonorgestrel (typically 1.5 mg, either as a single dose or two 0.75 mg doses) to be used if LAM prerequisites expire or are compromised before a long-term contraceptive method is initiated. Levonorgestrel is a synthetic progestogen that prevents pregnancy primarily by delaying or inhibiting ovulation. This specific strategy was evaluated in a randomized trial at Assiut University to increase the uptake of regular contraception and reduce unintended pregnancies in breastfeeding women.

Other names
LAM + LNG-ECEmergency Contraception as a Backup to Lactational Amenorrhea MethodLAM + LNG-EC-Assiut University-unintended pregnancy
02

Targets

PR (Progesterone receptor)

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