lidocaine + bupivacaine + epinephrine

Ankle SSB is a specific regional anesthetic combination used for single-shot peripheral nerve blocks to manage postoperative pain following ankle fracture surgery. Developed and studied by NYU Langone Health, this formulation consists of a mixture of lidocaine (a fast-acting local anesthetic), bupivacaine (a long-acting local anesthetic), and epinephrine (a vasoconstrictor used to prolong the block's duration and reduce systemic absorption). It is typically administered via injection around the target nerves to provide immediate and sustained analgesia during the early postoperative period. The combination leverages the rapid onset of lidocaine and the extended duration of bupivacaine, while epinephrine enhances the efficacy and safety profile by localizing the drugs at the site of injection.

Other names

Single Shot Peripheral Nerve Block