Drug intelligence / Profile preview

lidocaine + bupivacaine + fentanyl

Development stage
Unknown
Lead developer
AstraZeneca
Modality
Small Molecules
Administration
Epidural, Intrathecal
01

Overview

This is a combination of three drugs—lidocaine, bupivacaine, and fentanyl—used primarily for regional anesthesia and analgesia. Lidocaine and bupivacaine are amide-type local anesthetics that block sodium channels in neuronal membranes, inhibiting nerve impulse conduction to provide local or regional numbness. Fentanyl is a potent synthetic opioid agonist at the mu-opioid receptor, providing strong analgesic effects. The combination leverages the rapid onset of lidocaine, the prolonged duration of bupivacaine, and the synergistic pain relief from fentanyl. This mixture may be used in epidural or spinal anesthesia for surgical procedures or labor analgesia to achieve effective pain control with reduced doses of each component[1][2][5][6].

02

Targets

NaV alpha (Voltage-gated sodium channel alpha subunit family)MOR (Mu opioid receptor)

Beyond the preview

Go deeper on lidocaine + bupivacaine + fentanyl.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on lidocaine + bupivacaine + fentanyl.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call