Drug intelligence / Profile preview

lidocaine + bupivacaine + saline

Development stage: Unknown
Modality: Small Molecules
Administration: Infiltration, Nerve Block, Epidural

Overview

A combination of lidocaine (a fast-acting local anesthetic), bupivacaine (a long-acting local anesthetic), and saline (as a diluent). This mixture combines the rapid onset of lidocaine with the prolonged duration of bupivacaine to provide effective anesthesia and analgesia. It is used in various clinical applications including supraclavicular brachial plexus block, hand surgery, and labor analgesia. A common formulation involves mixing these components in specific ratios, sometimes buffered with sodium bicarbonate to neutralize pH and reduce injection discomfort.

Other names: lidocaine, bupivicaine and salinelidocaine + bupivicaine + saline

Targets

NaV (Voltage-gated sodium channels)

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