Drug intelligence / Profile preview

Lidocaine + Functional Microarray

Development stage
Unknown
Lead developer
University of Oklahoma
Modality
Small Molecules
Administration
Topical
01

Overview

Lidocaine + Functional Microarray (FMA) is a combination product consisting of a 4% lidocaine gel and a microneedle-based delivery device, developed by the University of Oklahoma. The FMA device is designed to create microscopic channels in the skin's stratum corneum, thereby bypassing the primary barrier to drug absorption and allowing the lidocaine gel to penetrate more rapidly and deeply into the dermis. This system is specifically being evaluated for its ability to provide fast-acting topical anesthesia for painful procedures such as venipuncture. Lidocaine, the active component, is a local anesthetic that works by blocking voltage-gated sodium channels in neuronal membranes, preventing the initiation and conduction of nerve impulses that transmit pain.

Other names
Microneedle-facilitated lidocaine application4% lidocaine gel application with functional microarray of needlesTopical 4% lidocaine gel
02

Targets

NaV (Voltage-gated sodium channels)

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