lidocaine + pethidine + propofol

A combination of three drugs commonly used in anesthesia and pain management: 1. **Lidocaine**: An amide-type local anesthetic that blocks sodium channels to prevent nerve impulse transmission, reducing pain sensation. It's also used to reduce pain on propofol injection[1][3]. 2. **Pethidine** (also known as meperidine): An opioid analgesic used for perioperative and chronic pain management[8]. 3. **Propofol**: A sedative-hypnotic agent used for induction and maintenance of anesthesia. It works by positively modulating the inhibitory function of GABA through GABA-A receptors[4]. When used in combination, these drugs can provide effective anesthesia and analgesia with potentially reduced doses of each individual component, which may minimize side effects while maintaining efficacy[5][7].