lidocaine 7% + tetracaine 7% cream

This refers to a specific topical anesthetic cream formulation containing 7% lidocaine and 7% tetracaine (LTTA) studied by Northwestern University for the management of procedural pain. The drug is a combination of an amide-type local anesthetic (lidocaine) and an ester-type local anesthetic (tetracaine), both of which function by reversibly blocking voltage-gated sodium channels in neuronal membranes. This blockade prevents the initiation and conduction of nerve impulses, providing localized anesthesia. In clinical research (IRB # STU00200401), this high-concentration formulation was evaluated for its efficacy in reducing pain during dermatologic laser procedures, such as Q-switched 532nm laser treatment for lentigines, comparing it against standard 2.5% lidocaine/2.5% prilocaine cream and placebo.

Other names

7% lidocaine/7% tetracaine topical anesthetic creamLTTA cream