Drug intelligence / Profile preview

liraglutide + insulin aspart

Development stage
Preclinical
Lead developer
Biogenomics
Modality
Recombinant Proteins and Enzymes, Peptides
Administration
Subcutaneous
01

Overview

Liraglutide + insulin aspart is a preclinical-stage combination therapy being developed by Biogenomics (India). It combines a biosimilar version of liraglutide, a long-acting glucagon-like peptide-1 (GLP-1) receptor agonist, with a biosimilar version of insulin aspart, a rapid-acting insulin analog. This recombinant protein combination is administered via subcutaneous injection and is designed to improve glycemic control in patients with Type 1 and Type 2 diabetes mellitus. By simultaneously targeting the GLP-1 receptor and the insulin receptor, the therapy aims to provide synergistic effects on blood glucose management while potentially reducing cardiovascular risk in patients with Type 2 diabetes. The product leverages Biogenomics' expertise in recombinant protein production and biosimilar development, utilizing their existing individual biosimilar components in a fixed-dose or co-administered format.

02

Targets

INSR (Insulin receptor)GLP1R (GLP-1R)

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