Drug intelligence / Profile preview

liraglutide + phentermine

Development stage
Preclinical
Lead developer
Novo Nordisk
Modality
Peptides, Small Molecules
Administration
Subcutaneous, Oral
01

Overview

Liraglutide + phentermine is a combination of two pharmaceutical agents used off-label for weight management in adults with obesity. Liraglutide is a glucagon-like peptide 1 receptor agonist that enhances glucose-dependent insulin secretion, suppresses glucagon secretion, delays gastric emptying, and reduces appetite. Phentermine is a sympathomimetic amine that acts as an appetite suppressant by stimulating the central nervous system to increase norepinephrine release and reduce hunger signals. The combination has been studied in clinical trials for its potential to augment weight loss beyond what is achieved with either agent alone; however, evidence suggests only modest additional benefit when added to ongoing liraglutide therapy after significant initial weight loss[1][3][4]. Both drugs are approved individually for obesity but not as a fixed-dose combination.

Other names
Saxenda + Adipex-PSaxenda + Lomairaliraglutide-phentermine
02

Targets

DAT (Dopamine plasma membrane transport protein)GLP1R (GLP-1R)SERT (Sodium-dependent serotonin transporter)NET (Norepinephrine Transporter)

Beyond the preview

Go deeper on liraglutide + phentermine.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on liraglutide + phentermine.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call