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low lactose milk + galactooligosaccharides

Development stage: Unknown
Modality: Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration: Oral

Overview

This novel milk formulation is produced through the enzymatic conversion of lactose into galacto-oligosaccharides (GOS) using a one-step in situ trans-galactosylation process. The resulting product is characterized by a low lactose content (approximately 1.7g per serving) and a high concentration of prebiotic GOS (approximately 9g per serving). The primary mechanism of action involves the modulation of the intestinal microbiota, specifically promoting the proliferation of beneficial *Bifidobacterium* species. Clinical research, including a 2025 double-blind controlled trial, indicates that regular consumption can significantly alter gut microbial abundance and related metabolic pathways, potentially offering benefits for gut health and the management of lactose intolerance symptoms.

Other names: GOS-enriched low-lactose milkin situ GOS milk

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