LSD + olanzapine

This is a non-standard, unbranded combination of two drugs: - **LSD (lysergic acid diethylamide)** is a classic psychedelic that acts primarily as an agonist at the serotonin 5-hydroxytryptamine receptor 2A (5-HT2A), leading to profound alterations in perception, mood, and cognition. It is not approved for any medical use in most countries but has been studied experimentally for various neuropsychiatric conditions. - **Olanzapine** is an atypical antipsychotic used primarily to treat schizophrenia and bipolar disorder. Its mechanism involves antagonism of multiple neurotransmitter receptors in the brain, notably dopamine D2 and serotonin 5-HT2A receptors[4][2]. Olanzapine can attenuate or block the psychoactive effects of LSD due to its potent antagonism at the 5-HT2A receptor[6]. There are no approved pharmaceutical products combining these two agents. The combination may be considered experimentally or off-label in research settings where olanzapine is used to manage or terminate psychedelic-induced symptoms.

Other names

LSD plus olanzapinelysergic acid diethylamide and olanzapine