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Lubristil + Air Optix Night & Day

Development stage: Discontinued
Lead developer: Alcon
Modality: Small Molecules
Administration: Ophthalmic

Overview

This combination regimen refers to the conventional treatment control arm used in clinical trials for neurotrophic keratopathy, specifically the Phase I/II trial NCT03084861 conducted by Banc de Sang i Teixits. The regimen consists of Lubristil, a lubricant eye drop (artificial tears) containing sodium hyaluronate, and Air Optix Night & Day, a silicone hydrogel therapeutic contact lens. Lubristil acts as an ocular lubricant to stabilize the tear film and hydrate the ocular surface, while the Air Optix Night & Day lens serves as a physical bandage to protect the compromised corneal epithelium from mechanical trauma and promote re-epithelialization in patients with stage 2 or 3 neurotrophic keratopathy.

Brand names: LubristilAir Optix Night & Day
Other names: conventional treatment-Banc de Sang i Teixits-neurotrophic keratopathyConventional treatment (artificial tears and therapeutic contact lens)

Targets

CD44 (CD44 antigen)

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