Drug intelligence / Profile preview

lutein + zeaxanthin + curcuminoids + vitamin D3

Development stage
Unknown
Lead developer
Bausch + Lomb
Modality
Small Molecules
Administration
Oral
01

Overview

A proprietary oral **combination dietary supplement** containing **lutein**, **zeaxanthin**, **curcuminoids** (from curcumin), and **vitamin D3**. Designed to target multifactorial dry eye disease and ocular surface inflammation, the formulation acts through several mechanisms: - **Lutein** and **zeaxanthin** are carotenoids concentrated in the macula, providing antioxidant protection against photo-oxidative stress and absorbing damaging blue light. - **Curcuminoids** (from curcumin) exhibit potent anti-inflammatory and antioxidant effects by suppressing cytokine-mediated inflammatory pathways and oxidative stress. - **Vitamin D3** offers immunomodulatory and anti-inflammatory activity, enhancing tear secretion and stabilizing tear film. The blend is micronized for enhanced bioavailability, and clinical studies demonstrate significant improvements in tear production, stability, tear osmolarity, and reduced ocular surface damage and inflammation in patients with mild to moderate dry eye symptoms. Its primary indication is **dry eye syndrome (DED)**, including improving tear volume, stabilizing tear film, and reducing ocular inflammation[1][2][4].

Brand names
Blink NutriTears
Other names
LCD

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