Drug intelligence / Profile preview

LY30410 (rivastigmine)

Development stage
Unknown
Lead developer
Luye Pharma
Modality
Small Molecules
Administration
Transdermal
01

Overview

LY30410 is a multi-day transdermal patch formulation of rivastigmine, developed by Luye Pharma Group using its proprietary Novel Drug Delivery System (NDDS). Rivastigmine is a carbamate derivative that acts as a reversible, dual inhibitor of both acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE). By inhibiting these enzymes, it prevents the breakdown of acetylcholine, thereby increasing its concentration in the brain and improving cholinergic function in patients with Alzheimer's dementia. Unlike the conventional once-daily patches, LY30410 is designed for twice-weekly administration, which aims to enhance patient adherence and provide more stable plasma concentrations of the drug. It has received marketing authorization in several European countries for the treatment of mild to moderate Alzheimer's disease.

Other names
Rivastigmine Multi-Day Transdermal PatchRivastigmine MD Patchtwice-weekly rivastigmine patch
02

Targets

AcetylcholinesteraseButyrylcholinesterase

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