lysine + butyrate

**Lysine + butyrate** is a combination of two compounds: **lysine**, an essential amino acid, and **butyrate**, a short-chain fatty acid with important cellular signaling roles. This compound, found as lysine butyrate, is designed to deliver butyrate systemically with improved bioavailability compared to other butyrate formulations. Butyrate acts mainly as a histone deacetylase inhibitor, G-protein coupled receptor (GPCR, e.g., GPR109A) agonist, and modulator of immune function; it enhances intestinal barrier function, exerts anti-inflammatory effects, supports energy metabolism, and modulates immune homeostasis. Lysine supports protein synthesis, collagen formation, and tissue repair. The combination aims to provide systemic benefits including improved gut health, balanced immunity, reduced inflammation, and increased metabolic/wellness parameters. Recent studies suggest lysine butyrate achieves higher plasma concentrations and more rapid systemic appearance compared to other butyrate salts or esters[1][2][3].

Brand names

BIOMEnd™

Other names

lysine butyrateL-lysine butyrateLysB