Drug intelligence / Profile preview

lysine-3,4-methylenedioxyamphetamine

Development stage
Phase 1
Lead developer
MiHKAL
Modality
Small Molecules
Administration
Oral
01

Overview

Lysine-3,4-methylenedioxyamphetamine (Lys-MDA) is a substituted amphetamine derivative with empathogenic effects. It acts as a prodrug for MDA with a slower onset of effects and longer duration of action. Lys-MDA is being investigated as a potential treatment for treatment-resistant depression and post-traumatic stress disorder.

Other names
Lys-MDAN-(L-lysinamidyl)-3,4-methylenedioxyamphetamine
02

Targets

SERT (Sodium-dependent serotonin transporter)NET (Norepinephrine Transporter)DAT (Dopamine plasma membrane transport protein)

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