Drug intelligence / Profile preview

lysozyme + cetylpyridine + lidocaine

Development stage
Phase 3
Lead developer
Bosnalijek
Modality
Recombinant Proteins and Enzymes, Small Molecules
Administration
Oral, Oromucosal, Topical
01

Overview

This is a **combination drug** composed of **lysozyme**, **cetylpyridine** (commonly used as cetylpyridinium chloride), and **lidocaine**. - **Lidocaine** is an amide-type local anesthetic that blocks sodium channels on neuronal membranes, producing reversible loss of sensation and pain relief at the site of application[5][7]. - **Cetylpyridine** (typically referenced as cetylpyridinium chloride, CPC) is a cationic quaternary ammonium compound with antiseptic, antibacterial, and antiviral properties, commonly used in oral care products for controlling bacterial growth, reducing gingivitis, and treating sore throat[2][4][6]. - **Lysozyme** is an enzyme with natural antibacterial properties, capable of breaking down bacterial cell walls. It is commonly utilized in oral and mucosal treatments for its antimicrobial action (supported by general pharmaceutical literature, but not specifically referenced in the search results). The combination is designed primarily for **oromucosal application**, targeting symptoms such as sore throat, oral pain, minor infections, and oral mucosal lesions. Commonly, such combinations are found in lozenge or gel formulations, with the lidocaine providing rapid local anesthesia and cetylpyridine (chloride) and lysozyme contributing antiseptic and antibacterial effects; the combination is generally regarded as safe for short-term topical oral use[1][2][5][7].

Brand names
Lysobact Complete Spray
Other names
lysozyme + cetylpyridine + lidocaine
02

Targets

NaV (Voltage-gated sodium channels)

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