Drug intelligence / Profile preview

magnesium + ascorbic acid

Development stage
Approved
Lead developer
McGuff Pharmaceuticals
Modality
Small Molecules
Administration
Oral
01

Overview

This is a **combination of magnesium (an essential mineral) and ascorbic acid (vitamin C)**. These two ingredients are often co-administered as dietary supplements, sometimes as **magnesium ascorbate**, a buffered salt form that provides both nutrients. Magnesium is vital for hundreds of biochemical reactions, including nerve and muscle function and energy production. Ascorbic acid (vitamin C) is an antioxidant necessary for collagen synthesis, immune support, and as a cofactor in enzymatic reactions. Some research suggests that magnesium may enhance cellular uptake and the **anticancer effects of ascorbic acid** by upregulating or activating vitamin C transporters (notably SVCT-2), leading to synergistic effects—particularly in cancer cell lines and animal models. The primary indications for this combination are dietary supplementation for deficiency or increased requirement, immune system support, and investigational anticancer effects[4][6].

Other names
magnesium plus ascorbic acidmagnesium and vitamin Cmagnesium ascorbate
02

Targets

SLC23A2 (Sodium-dependent vitamin C transporter 2)TET1 (Methylcytosine dioxygenase TET1)

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