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magnesium chloride + dextrose monohydrate + sodium lactate + sodium chloride + calcium chloride

Development stage: Approved
Lead developer: Fresenius Medical Care
Modality: Small Molecules
Administration: Intraperitoneal

Overview

Magnesium chloride + dextrose monohydrate + sodium lactate + sodium chloride + calcium chloride is a **multi-electrolyte peritoneal dialysis solution** marketed as **Delflex** by Fresenius Medical Care for patients with chronic kidney failure maintained on peritoneal dialysis. The formulation contains dextrose monohydrate as the osmotic agent together with sodium chloride, sodium lactate, calcium chloride, and magnesium chloride to create a dialysate that exchanges solutes and water across the peritoneal membrane. Its therapeutic effect is primarily physicochemical rather than receptor-mediated: the hyperosmolar dextrose solution promotes ultrafiltration, while the electrolyte and lactate components help maintain dialysate composition and buffering during dialysis. It is administered intraperitoneally as a sterile solution and has been marketed in multiple concentrations and ionic variants, including low magnesium and low calcium presentations.

Brand names: Delflex
Other names: peritoneal dialysis solutionmagnesium chloride + dextrose monohydrate + sodium lactate + sodium chloride + calcium chloride

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