Drug intelligence / Profile preview

magnesium chloride + potassium chloride + sodium gluconate + sodium acetate + sodium chloride

Development stage
Unknown
Lead developer
Takeda
Modality
Small Molecules
Administration
Intravenous, Topical
01

Overview

magnesium chloride + potassium chloride + sodium gluconate + sodium acetate + sodium chloride is a sterile, nonpyrogenic, isotonic balanced electrolyte solution used primarily for intravenous fluid and electrolyte replacement and, in some product presentations, for general irrigation, washing, and rinsing. Marketed under brands including Plasma-Lyte A, Plasma-Lyte 148, and Physiolyte, it is manufactured by companies such as Baxter and B. Braun. The formulation contains inorganic electrolyte salts that replenish sodium, potassium, magnesium, and chloride, while acetate and gluconate are metabolized to bicarbonate precursors and provide an alkalinizing effect. With a near-physiologic pH and osmolarity approximating plasma, it is used in adults and pediatric patients as a source of water and electrolytes, for dehydration and electrolyte imbalance, and as an alkalinizing agent.

Brand names
Plasma-Lyte APlasma-Lyte 148Plasma-Lyte148Plasma-Lyte-148Physiolyte
Other names
multiple electrolytes injection type 1multiple electrolytes injection type 1 pH 7.4multiple electrolytes injection type 1 pH 5.5physiological irrigating solution

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