Drug intelligence / Profile preview

magnesium citrate + bisacodyl

Development stage
Unknown
Modality
Small Molecules
Administration
Oral, Rectal
01

Overview

A combination of magnesium citrate and bisacodyl is used primarily as a bowel preparation regimen before colonoscopy or other medical procedures requiring an empty colon. Magnesium citrate acts as an osmotic laxative by drawing water into the intestines through its high osmolality, which increases fluid in the colonic lumen and stimulates peristalsis. Bisacodyl is a stimulant laxative that works by directly stimulating enteric nerves to increase intestinal motility and secretion. The combination provides effective cleansing of the colon with improved patient tolerance compared to some alternatives such as castor oil. This regimen is available in various over-the-counter kits and generic forms[2][3][4][7].

Brand names
LoSo Prep KitTridrate Bowel Evacuant KitsDulcolax Bowel Prep Kit
Other names
bisacodyl/magnesium citratemagnesium citrate-bisacodyl regimen

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