Drug intelligence / Profile preview

magnesium citrate + potassium citrate

Development stage
Unknown
Lead developer
Stadchem
Modality
Small Molecules
Administration
Oral
01

Overview

K-2 (also known as K-2 Syrup or K-2 Sugar Free Solution) is an oral fixed-dose combination of magnesium citrate and potassium citrate developed by Stadchem. It is indicated for the prevention of kidney stones (specifically uric acid and calcium oxalate stones) and the management of renal tubular acidosis. Potassium citrate is metabolized to bicarbonate in the liver, which increases systemic and urinary pH, thereby alkalinizing the urine and increasing the solubility of uric acid and calcium salts. Magnesium citrate provides magnesium ions that bind to oxalate in the gastrointestinal tract, reducing its absorption and subsequent urinary excretion, while also directly inhibiting the crystallization and growth of calcium oxalate in the urine.

Brand names
K-2K2K 2K-2 Sugar Free SolutionK2 Sugar Free SolutionK 2 Sugar Free SolutionK-2 SyrupK2 SyrupK 2 Syrup
Other names
magnesium citrate + potassium citratepotassium citrate + magnesium citrate

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