magnesium hydroxide + aluminum hydroxide

Magnesium aluminum hydroxide is a combination antacid consisting of magnesium hydroxide and aluminum hydroxide. In the clinical research context of Isfahan University of Medical Sciences, it is utilized as a topical oral rinse, often as a primary component of a "magic mouthwash" formulation, for the management of cancer treatment-induced stomatitis (oral mucositis). Its therapeutic effect in this setting is primarily attributed to its role as a mucosal protective agent; it provides a physical coating over the oral mucosa that protects ulcerated tissues and exposed nerve endings from chemical and mechanical irritation, thereby reducing pain. While its systemic use is intended for the neutralization of gastric acid, its topical application in the oral cavity leverages its soothing and barrier-forming properties to alleviate the symptoms of severe mucositis in patients undergoing head and neck cancer therapy.

Brand names

MaaloxMylantaGelusil

Other names

Magnesium aluminum hydroxideMagnesium aluminum hydroxide suspensionAl-Mg suspension