Drug intelligence / Profile preview

magnesium sulfate + morphine

Development stage
Approved
Modality
Small Molecules
Administration
Intravenous, Intrathecal
01

Overview

A combination of magnesium sulfate and morphine used for pain management. Magnesium sulfate potentiates the analgesic effects of morphine, allowing for better pain control with potentially lower doses of morphine. Magnesium sulfate acts as an NMDA receptor antagonist while morphine is an opioid agonist that binds to opioid receptors in the central nervous system.

Other names
magnesium sulfatemorphine
02

Targets

NMDAR (Glutamate receptor ionotropic, NMDA)MOR (Mu opioid receptor)

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