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Maharishi Amrit Kalash (MAK) 4+5 is a multi-component Ayurvedic herbal antioxidant preparation consisting of two distinct formulations: MAK-4, a herbal fruit concentrate (paste), and MAK-5, a herbal extract tablet. These preparations contain a complex mixture of over 40 herbs, including *Phyllanthus emblica* (Amla) and *Terminalia chebula*, which are rich in polyphenols, bioflavonoids, and vitamin C. MAK is primarily studied for its potent free-radical scavenging and antioxidant properties, which are hypothesized to reduce oxidative stress and inhibit lipid peroxidation. By mitigating these processes, the supplement is intended to slow the progression of atherosclerosis and other cardiovascular diseases. Clinical research supported by the National Center for Complementary and Integrative Health (NCCIH) has specifically evaluated MAK 4+5 for its potential cardioprotective effects in high-risk populations, such as older African Americans.
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