measles vaccine + mumps vaccine + rubella vaccine

The measles, mumps, and rubella (MMR) vaccine is a trivalent live attenuated biologic vaccine designed to provide active immunity against measles, mumps, and rubella. This specific formulation, containing the Moraten measles strain, the Jeryl Lynn mumps strain, and the Wistar RA 27/3 rubella strain, was evaluated in a Phase 4 clinical trial (NCT00731965) led by Dr. N.M. Wulffraat at the University Medical Centre Utrecht. The study specifically investigated the safety and immunogenicity of an MMR booster in children aged 4 to 9 years with Juvenile Idiopathic Arthritis (JIA), including those on immunosuppressive therapy such as methotrexate. The trial demonstrated that the booster vaccination did not exacerbate JIA disease activity and successfully induced protective antibody levels, confirming its safety and efficacy in this patient population.

Brand names

M-M-R IIMMR-II

Other names

MMR vaccinelive attenuated measles-mumps-rubella vaccinemeasles, mumps, and rubella virus vaccine live