Drug intelligence / Profile preview

Melatonin + Hyaluronic acid

Development stage
Unknown
Lead developer
Concordia Dent
Modality
Small Molecules
Administration
Topical, Oral, Intraarticular, Subcutaneous, Intradermal, Ophthalmic
01

Overview

Melatonin + Hyaluronic acid is a combination product comprising melatonin, a naturally occurring hormone, and hyaluronic acid, a glycosaminoglycan. Melatonin primarily functions as an agonist for MT1 and MT2 G protein-coupled receptors, regulating circadian rhythms and promoting sleep. It also exhibits significant antioxidant and anti-inflammatory properties. Hyaluronic acid is a key component of the extracellular matrix, known for its ability to attract and retain water, providing lubrication, cushioning, and structural support. It also plays roles in cell migration, proliferation, and tissue repair, often interacting with the CD44 receptor. The combination is being investigated for synergistic effects, particularly in topical applications for conditions such as periodontal disease and bone healing, leveraging melatonin's antioxidant and anti-inflammatory actions with hyaluronic acid's tissue-supporting and regenerative capabilities.

Other names
TM-Melatonin-Hyaluronic acidMEL-HA mixture
02

Targets

CD44 (CD44 antigen)MTNR1B (Melatonin Receptor 2)MTNR1A (MT1)

Beyond the preview

Go deeper on Melatonin + Hyaluronic acid.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on Melatonin + Hyaluronic acid.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call