Drug intelligence / Profile preview

meloxicam + glucosamine

Development stage
Unknown
Lead developer
Zodiac Pharmaceutical Products
Modality
Small Molecules
Administration
Oral
01

Overview

meloxicam + glucosamine is a fixed-dose combination therapy developed by Zodiac Produtos Farmaceuticos S.A. for the management of osteoarthritis, particularly of the knee. It combines meloxicam, a non-steroidal anti-inflammatory drug (NSAID) that preferentially inhibits cyclooxygenase-2 (COX-2) to reduce pain and inflammation, with glucosamine, an amino sugar that serves as a precursor for glycosaminoglycans in joint cartilage. The combination aims to provide rapid symptomatic relief through meloxicam's analgesic properties while utilizing glucosamine to support cartilage health and potentially modify the progression of the disease. This combination is specifically formulated to address both the inflammatory symptoms and the underlying structural degradation associated with osteoarthritis.

Brand names
Mobiflex G
Other names
meloxicam/glucosamineglucosamine/meloxicam
02

Targets

MMP12 (Macrophage Metalloelastase)PGHS-1 (Prostaglandin G/H Synthase 1)PLA2 (Phospholipase A2 group IID)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)

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