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Drug intelligence / Profile preview
meningococcal A + C vaccine
- Development stage
- Phase 1
- Lead developer
- Serum Institute of India
- Modality
- Vaccines & Immunotherapeutics
- Administration
- Intramuscular, Subcutaneous
01
Overview
The meningococcal A + C vaccine is a combination vaccine designed to protect against invasive disease caused by *Neisseria meningitidis* serogroups A and C. It is typically formulated as a polysaccharide or conjugate vaccine, containing purified capsular polysaccharides from the respective serogroups. The mechanism of action involves stimulating the immune system to produce antibodies against the capsular antigens of *N. meningitidis* serogroups A and C, thereby providing immunity and preventing diseases such as bacterial meningitis and sepsis caused by these strains. The primary indication for this vaccine is prevention of invasive meningococcal disease in populations at risk, including during outbreaks or in regions where these serogroups are prevalent[5]. Multiple manufacturers produce this type of combination vaccine for use globally.
- Brand names
- Menomune
- Other names
- meningococcal polysaccharide vaccine A + CMenACAC meningitis vaccine
02
Targets
NmA CPS (Neisseria meningitidis group A capsular polysaccharide)Neisseria meningitidis group C capsular polysaccharide
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