Drug intelligence / Profile preview

meningococcal groups A, C, Y, and W-135 polysaccharide vaccine

Development stage
Approved
Lead developer
Parent
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

Meningococcal groups A, C, Y, and W-135 polysaccharide vaccine is an active immunizing agent used to prevent infection by specific groups of meningococcal bacteria. The vaccine contains purified capsular polysaccharide antigens extracted from Neisseria meningitidis serogroups A, C, Y, and W-135. It works by stimulating the body to produce antibodies against these bacterial groups, providing protection against meningococcal meningitis and meningococcemia. Available in both polysaccharide and conjugate formulations, with conjugate versions linked to carrier proteins such as diphtheria toxoid (MenACWY-D), CRM197 protein (MenACWY-CRM), or tetanus toxoid (MenACWY-TT) for enhanced immunogenicity.

Brand names
MenactraMenveoMenQuadfiNmVac4-A/C/Y/W-135
Other names
MenACWYMenACWY-DMenACWY-CRMMenACWY-TTACYW135 group meningococcal polysaccharide vaccineACYW-135 group meningococcal polysaccharide vaccineACYW 135 group meningococcal polysaccharide vaccine
02

Targets

NmA CPS (Neisseria meningitidis group A capsular polysaccharide)Neisseria meningitidis group C capsular polysaccharideMenW CPS (Neisseria meningitidis serogroup W capsular polysaccharide)Group Y CPS (Neisseria meningitidis group Y capsular polysaccharide)

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