Drug intelligence / Profile preview

meningococcal polysaccharide diphtheria conjugate vaccine (Sanofi)

Development stage
Approved
Lead developer
Sanofi Pasteur
Modality
Recombinant Proteins and Enzymes, Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

Meningococcal polysaccharide diphtheria conjugate vaccine is an active immunizing agent used to prevent invasive disease caused by Neisseria meningitidis serogroups A, C, Y, and W-135. The vaccine contains capsular polysaccharides from these four serogroups of N. meningitidis that are individually conjugated to a carrier protein—diphtheria toxoid—which enhances the immune response by promoting T-cell dependent immunity. This results in improved immunogenicity compared to plain polysaccharide vaccines and provides longer-lasting protection with immune memory. It is administered intramuscularly and indicated for use in children as young as 2 months (Menveo) or 9 months (Menactra), up through adults aged 55 years[1][3][5][7]. The primary indication is prevention of invasive meningococcal disease.

Brand names
MenactraMenveo
Other names
Meningococcal (Groups A, C, Y and W-135) Polysaccharide Diphtheria Toxoid Conjugate Vaccinemeningococcal polysaccharide vaccine diphtheria conjugate
02

Targets

Neuraminidase

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