Drug intelligence / Profile preview

meningococcal polysaccharide diphtheria conjugate vaccine (Sanofi)

Development stage
Approved
Lead developer
Parent
Modality
Vaccines & Immunotherapeutics, Recombinant Proteins and Enzymes
Administration
Intramuscular
01

Overview

Meningococcal polysaccharide diphtheria conjugate vaccine is an active immunizing agent used to prevent invasive disease caused by Neisseria meningitidis serogroups A, C, Y, and W-135. The vaccine contains capsular polysaccharides from these four serogroups of N. meningitidis that are individually conjugated to a carrier protein—diphtheria toxoid—which enhances the immune response by promoting T-cell dependent immunity. This results in improved immunogenicity compared to plain polysaccharide vaccines and provides longer-lasting protection with immune memory. It is administered intramuscularly and indicated for use in children as young as 2 months (Menveo) or 9 months (Menactra), up through adults aged 55 years[1][3][5][7]. The primary indication is prevention of invasive meningococcal disease.

Brand names
MenactraMenveo
Other names
Meningococcal (Groups A, C, Y and W-135) Polysaccharide Diphtheria Toxoid Conjugate Vaccinemeningococcal polysaccharide vaccine diphtheria conjugate
02

Targets

Neuraminidase

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