Drug intelligence / Profile preview

meningococcal polysaccharide vaccine, groups A, C, Y and W135

Development stage
Unknown
Lead developer
Walvax Biotechnology
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

MPV-ACYW135 is a quadrivalent meningococcal polysaccharide vaccine (MPV) designed to provide active immunization against invasive meningococcal disease caused by *Neisseria meningitidis* serogroups A, C, Y, and W135. Developed by Beijing Minhai Biotechnology and other Chinese manufacturers, the vaccine contains purified capsular polysaccharides from each of the four serogroups. It induces a T-cell independent immune response, resulting in the production of serogroup-specific bactericidal antibodies. This polysaccharide version has been licensed and widely used in China since 2012, primarily for older children and adults, while conjugate versions (MCV-ACYW135) are developed for broader use including infants.

Brand names
Yuxi Walvax MPV ACYWMPV ACYW
Other names
Meningococcal (A, C, Y and W135) Polysaccharide VaccineMPV-ACYW135 vaccineMPV-ACYW-135 vaccineMPV-ACYW 135 vaccine
02

Targets

MenW CPS (Neisseria meningitidis serogroup W capsular polysaccharide)Neisseria meningitidis group C capsular polysaccharideNmA CPS (Neisseria meningitidis group A capsular polysaccharide)Group Y CPS (Neisseria meningitidis group Y capsular polysaccharide)

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