Drug intelligence / Profile preview

Menitorix + Infanrix Penta

Development stage
Unknown
Lead developer
GSK
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

IH + Hib-MenC/NVC refers to a combination vaccine regimen consisting of the co-administration of two GlaxoSmithKline (GSK) products: **Menitorix** and **Infanrix Penta**. Menitorix is a combined conjugate vaccine containing Haemophilus influenzae type b (Hib) and Neisseria meningitidis serogroup C (MenC) antigens, both conjugated to a tetanus toxoid carrier. Infanrix Penta is a pentavalent vaccine that protects against diphtheria, tetanus, acellular pertussis (DTPa), hepatitis B (HBV), and inactivated poliovirus (IPV). This combination regimen is used in pediatric immunization schedules to provide comprehensive protection against seven infectious diseases. It was evaluated in Phase 3 clinical trials to demonstrate that the co-administration of these vaccines is safe and maintains the immunogenicity of all individual components compared to other standard-of-care combinations like Infanrix Hexa.

Brand names
MenitorixInfanrix Penta
Other names
Hib-MenC-TT co-administered with DTPa-HBV-IPVCombined Hib-MenC vaccine co-administered with DTPa-HBV-IPV vaccine
02

Targets

PRNP (Cellular Prion Protein)Neisseria meningitidis group C capsular polysaccharideHBsAg (Hepatitis B surface antigen)TT (Tetanus toxoid)

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