Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
menthol + tretinoin + zinc oxide
- Development stage
- Unknown
- Lead developer
- Patchwerx Labs
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
Menthol + tretinoin + zinc oxide is a topical combination pharmaceutical product marketed as **DERMAWERX ZMT PAK**. It is a kit-based formulation manufactured for Rouses Point Pharmaceuticals that combines tretinoin, a small-molecule retinoid used as the principal anti-acne agent, with menthol as an external analgesic and anti-itch component and zinc oxide as a skin protectant. In this combination, tretinoin drives the therapeutic effect in acne vulgaris by normalizing epidermal differentiation and accelerating turnover of follicular epithelial cells, thereby promoting comedolysis and reducing acne lesion formation, while menthol and zinc oxide provide supportive topical symptom-relief and barrier-protective functions. The tretinoin component is applied once daily at bedtime to affected skin, and the overall product is intended for external topical use only.
- Brand names
- DERMAWERX ZMT PAK
- Other names
- menthol + tretinoin + zinc oxidezinc oxide + menthol + tretinoin
02
Targets
RARA (Retinoic acid receptor alpha)TRPM8 (Transient receptor potential cation channel subfamily M member 8)RXRA (Retinoid X receptor alpha)RARG (Retinoic acid receptor gamma)RARB (Retinoic acid receptor beta)
Beyond the preview
Go deeper on menthol + tretinoin + zinc oxide.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on menthol + tretinoin + zinc oxide.