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Drug intelligence / Profile preview
mepivacaine hydrochloride + articaine hydrochloride
- Development stage
- Unknown
- Lead developer
- Kodak
- Modality
- Small Molecules
- Administration
- Infiltration, Nerve Block
01
Overview
This combination involves two local anesthetics, **mepivacaine hydrochloride** and **articaine hydrochloride**, used for dental procedures. **Mepivacaine** is an amide local anesthetic with a rapid onset and medium duration, often used in infiltration and nerve block techniques. **Articaine** is also an amide local anesthetic known for its fast onset and long duration, commonly used in dental procedures. Both drugs work by blocking nerve impulses, thereby providing local anesthesia. The combination may enhance the effectiveness of anesthesia in certain dental procedures.
02
Targets
SCN5A (Sodium channel protein type 5 subunit alpha)NaV (Voltage-gated sodium channels)
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