Drug intelligence / Profile preview

mepyramine + sodium benzoate

Development stage
Unknown
Lead developer
Laboratoires Elerté
Modality
Small Molecules
Administration
Oral
01

Overview

FluiSédal is a combination pharmaceutical product developed by Laboratoires Élerté for the treatment of respiratory tract conditions, specifically non-productive coughs. The formulation consists of mepyramine maleate, a first-generation H1-antihistamine, and sodium benzoate. Mepyramine acts as an H1-receptor antagonist, providing antitussive and sedative effects that are particularly useful for nocturnal coughs. Sodium benzoate is traditionally included for its mild bronchial fluidifying properties, intended to assist in the management of respiratory secretions. This product is currently marketed as FluiSédal sans prométhazine to distinguish it from earlier versions that included promethazine, which has a more significant side-effect profile. It is primarily used in the symptomatic relief of dry, irritating coughs in both adults and children.

Brand names
FluiSédalFluiSédal sans prométhazine
Other names
FluiSédal sans prométhazinemepyramine maleate + sodium benzoate
02

Targets

HRH1 (Histamine H1 Receptor)

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