Drug intelligence / Profile preview

mequitazine + guaifenesin + sodium benzoate

Development stage
Unknown
Lead developer
Laboratoires Elerté
Modality
Small Molecules
Administration
Oral
01

Overview

FluiSédal is an oral syrup formulation developed by Laboratoire des Réalisations Thérapeutiques ELERTE for the management of respiratory symptoms associated with ear, nose, and throat (ENT) disorders. It is a combination product containing mequitazine, guaifenesin, and sodium benzoate. Mequitazine is a first-generation H1-antihistamine that provides symptomatic relief for coughs with an allergic component by acting as a selective H1-receptor antagonist. Guaifenesin and sodium benzoate function as expectorants; guaifenesin reduces the viscosity of bronchial secretions to facilitate clearance, while sodium benzoate acts as a mild stimulant expectorant. This specific version of FluiSédal is distinguished by the absence of promethazine, utilizing mequitazine as the antihistamine component instead. It is approved for the symptomatic treatment of bothersome non-productive and productive coughs, particularly those exacerbated by allergies.

Brand names
FluiSédal
Other names
FluiSédal without promethazine
02

Targets

mAChR (Muscarinic acetylcholine receptors)HRH1 (Histamine H1 Receptor)

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