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Mesenchymal stem cells (Hospital Znojmo)

Development stage: Unknown
Lead developer: Nemocnice Znojmo
Modality: Stem Cell Therapies → Cell Therapies
Administration: Local

Overview

Mesenchymal stem cells (MSCs) derived from bone marrow concentrate are being evaluated by Hospital Znojmo for their potential to enhance tendon-to-bone healing in patients undergoing reconstruction surgery for chronic rotator cuff tears, specifically supraspinatus muscle lesions. The therapy involves the application of concentrated autologous bone marrow-derived MSCs directly into the supraspinatus footprint during surgical repair. The mechanism of action relies on the regenerative, anti-inflammatory, and immunomodulatory properties of MSCs, which are hypothesized to improve the structural integrity and biological healing of the sutured tendon to the humerus.

Other names: Concentrated bone marrow stem cellsMSCsBone marrow-derived mesenchymal stem cells

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