Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
metadoxine + silymarin
- Development stage
- Unknown
- Lead developer
- Aganit Pharma
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Dwenit Forte is a branded generic fixed-dose combination drug containing **metadoxine** and **silymarin**, marketed by **Aganit Pharma**. Metadoxine is a hepatoprotective agent that enhances the metabolism of alcohol by increasing the activity of acetaldehyde dehydrogenase and alcohol dehydrogenase, thereby reducing the duration of alcohol intoxication and the risk of liver damage. Silymarin, a flavonolignan complex extracted from milk thistle (*Silybum marianum*), acts as a potent antioxidant, scavenging free radicals and stabilizing the cell membranes of hepatocytes to prevent toxin entry and promote liver regeneration. This combination is primarily used for the treatment of alcoholic liver disease, fatty liver, and chronic inflammatory liver conditions.
- Brand names
- Dwenit Forte
- Other names
- metadoxine + silymarin
02
Targets
ADH (Alcohol dehydrogenase family)Pol I (RNA polymerase I)ALDH2 (Mitochondrial Aldehyde Dehydrogenase)ER (Estrogen receptor)
Beyond the preview
Go deeper on metadoxine + silymarin.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on metadoxine + silymarin.