methenamine + sodium phosphate + phenyl salicylate + methylene blue + hyoscyamine

This combination drug is an oral medication indicated for the treatment of symptoms associated with lower urinary tract infections and irritations, such as pain, burning, and frequency. It is also used to relieve discomfort following diagnostic procedures. The formulation contains five active components: methenamine, which acts as a prodrug that converts to the bactericidal agent formaldehyde in acidic urine; sodium phosphate, which serves as a urinary acidifier to facilitate methenamine's conversion; hyoscyamine, an antispasmodic that antagonizes muscarinic acetylcholine receptors to reduce bladder spasms; phenyl salicylate, which provides mild analgesic and antiseptic effects; and methylene blue, a weak antiseptic. This multi-modal approach addresses both the underlying bacterial presence and the symptomatic spasms and pain associated with urinary tract conditions.

Brand names

Uro-MPUretron DSUrogesic BlueUtira-CUrylUro-BlueVilamit MBHyophenPhosphasalUro-LUrophen MBUstell

Other names

methenamine + sodium phosphate monobasic + phenyl salicylate + methylene blue + hyoscyamine sulfate