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methyl 1-(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}benzoyl)piperidine-4-carboxylate

Development stage
Unknown
Modality
Small Molecules
01

Overview

This compound is a synthetic small molecule belonging to the class of organic compounds known as 1-benzoylpiperidines. It features a piperidine ring substituted with a benzoyl group that is further modified by a (2,4-diaminopteridin-6-yl)methyl(methyl)amino moiety and an esterified carboxylic acid at the piperidine's fourth position. The structure is related to antifolate agents and pteridine derivatives but does not correspond to any approved pharmaceutical drug or widely recognized clinical candidate. Its mechanism of action has not been explicitly described in public databases; however, structurally similar compounds often act as inhibitors of folate-dependent enzymes such as dihydrofolate reductase or pteridine reductase. This compound appears in chemical and experimental drug databases but lacks evidence for clinical development or therapeutic use[1][3][6].

Other names
METHYL 1-(4-{[(2,4-DIAMINOPTERIDIN-6-YL)METHYL](METHYL)AMINO}BENZOYL)PIPERIDINE-4-CARBOXYLATE

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