Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
methyl salicylate + menthol
- Development stage
- Unknown
- Modality
- Classical Binding Small Molecules → Small Molecules
- Administration
- Topical
01
Overview
Methyl salicylate + menthol is a topical combination drug used to relieve minor pain associated with arthritis, backache, muscle strains, sprains, bruises, and cramps. It acts as a topical analgesic by combining two counterirritants: menthol and methyl salicylate. Menthol produces a cooling sensation followed by vasodilation (widening of blood vessels), which can enhance the penetration of other drugs through the skin and provide an analgesic effect. Methyl salicylate is a derivative of salicylic acid that inhibits cyclooxygenase enzymes (prostaglandin G/H synthase 1 and 2), reducing prostaglandin formation locally to decrease inflammation and pain. The combined action interferes with pain signal transmission in nerves by creating sensations of warmth or coolness at the application site[1][3][4][5].
- Brand names
- BenalgThera-GesicAnalgesic BalmBengay Arthritis Extra StrengthBengay OriginalBuckley's Pain Relief Rub
- Other names
- menthol and methyl salicylate
02
Targets
PTGS2 (Prostaglandin-Endoperoxide Synthase 2)GABRR (GABA-A receptor subunit rho)PGHS-1 (Prostaglandin G/H Synthase 1)
Beyond the preview
Go deeper on methyl salicylate + menthol.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on methyl salicylate + menthol.