Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
methylprednisolone + bronchodilators + inhaled corticosteroids + antiviral prophylaxis
- Development stage
- Unknown
- Lead developer
- NYU Langone Health
- Modality
- Small Molecules
- Administration
- Oral, Inhalation
01
Overview
This refers to a specific supportive care medication regimen administered to patients following the injection of subcutaneous daratumumab (Darzalex Faspro) in a Phase 2 clinical trial (NCT04916002) for STK11/LKB1-mutated non-small cell lung cancer (NSCLC). The regimen, established by NYU Langone Health, includes oral methylprednisolone (20 mg) for two days to mitigate delayed infusion-related reactions, bronchodilators and inhaled corticosteroids for patients with a history of chronic obstructive pulmonary disease (COPD), and antiviral prophylaxis to prevent herpes zoster reactivation. This combination is used to manage the safety profile of CD38-targeted therapy in this specific patient population.
- Other names
- Post-Intervention Medication
02
Targets
GR (Glucocorticoid receptor)
Beyond the preview
Go deeper on methylprednisolone + bronchodilators + inhaled corticosteroids + antiviral prophylaxis.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on methylprednisolone + bronchodilators + inhaled corticosteroids + antiviral prophylaxis.