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methylprednisolone acetate + isopropyl alcohol + povidone-iodine + lidocaine hydrochloride
- Development stage
- Preclinical
- Lead developer
- Pfizer
- Modality
- Small Molecules
- Administration
- Intramuscular, Intraarticular, Intralesional, Parenteral
01
Overview
Methylprednisolone acetate + isopropyl alcohol + povidone-iodine + lidocaine hydrochloride is a corticosteroid combination injection kit marketed as **Dyural L Kit**. The therapeutic core is **methylprednisolone acetate**, a depot synthetic glucocorticoid that exerts anti-inflammatory and immunosuppressive effects primarily through activation of the **glucocorticoid receptor** and downstream suppression of inflammatory gene transcription; **lidocaine hydrochloride** provides local anesthetic activity through blockade of voltage-gated sodium channels, while **isopropyl alcohol** and **povidone-iodine** serve antiseptic preparation roles within the kit. The product is intended for intramuscular, intra-articular, soft tissue, or intralesional administration in a broad set of inflammatory, allergic, dermatologic, rheumatologic, hematologic, autoimmune, and neoplastic conditions aligned with methylprednisolone acetate injectable suspension use. This is a specific multi-component kit formulation rather than plain methylprednisolone acetate alone, and the kit formulation itself has been described as not FDA approved as safe and effective.
- Brand names
- Dyural L Kit
- Other names
- methylprednisolone acetate + isopropyl alcohol + povidone-iodine + lidocaine hydrochloride
02
Targets
NaV (Voltage-gated sodium channels)GR (Glucocorticoid receptor)
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