Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
metoclopramide + ketorolac
- Development stage
- Unknown
- Modality
- Small Molecules
- Administration
- Intravenous, Intramuscular
01
Overview
A combination medication consisting of metoclopramide and ketorolac used primarily for the treatment of acute migraine headaches in emergency department settings. This combination is sometimes referred to as part of a "migraine cocktail." Metoclopramide is an antiemetic and prokinetic agent that works by blocking dopamine receptors and stimulating gastrointestinal motility. Ketorolac is a non-steroidal anti-inflammatory drug (NSAID) with potent analgesic, anti-inflammatory, and antipyretic properties. Research on the combination's effectiveness shows varying results, with some studies in children failing to show improved pain intensity compared to metoclopramide monotherapy.
02
Targets
DRD2 (Dopamine D2 Receptor)mAChR (Muscarinic acetylcholine receptors)PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)HTR3A (5-hydroxytryptamine receptor 3A)HTR4 (5-Hydroxytryptamine receptor 4)
Beyond the preview
Go deeper on metoclopramide + ketorolac.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on metoclopramide + ketorolac.