metoprolol + amlodipine

Metoprolol + amlodipine is a fixed-dose combination of two antihypertensive agents used primarily for the treatment of hypertension (high blood pressure) and angina pectoris (chest pain). Metoprolol is a beta-blocker that selectively blocks beta1 adrenergic receptor in the heart, reducing heart rate and cardiac output. Amlodipine is a calcium channel blocker that inhibits calcium ion influx into vascular smooth muscle and cardiac muscle, leading to vasodilation and reduced peripheral vascular resistance. Together, these drugs lower blood pressure more effectively than either agent alone, improve treatment adherence by combining two medications into one pill, and reduce the risk of cardiovascular events such as stroke or heart attack[1][3][4][5]. The combination has been shown to be safe, well-tolerated, and effective in clinical studies[3][8].

Brand names

Prolomet AMAmtas-MMetpure-AMAmlovas-MAmlopin-MVinicor-AMStarpress-AMEmbeta AMAmlong MT

Other names

amlodipine + metoprolol succinate