metoprolol succinate + hydrochlorothiazide

Metoprolol succinate + hydrochlorothiazide is a fixed-dose combination of two antihypertensive agents: metoprolol succinate, a selective beta-1 adrenergic receptor blocker (beta-blocker), and hydrochlorothiazide, a thiazide diuretic. Metoprolol works by reducing heart rate and cardiac output, thereby lowering blood pressure. Hydrochlorothiazide lowers blood pressure by promoting the excretion of sodium and water through the kidneys, which reduces plasma volume. This combination is primarily indicated for the treatment of hypertension (high blood pressure) to reduce the risk of cardiovascular events such as heart attack or stroke[1][2][3][4][5]. The combination may be used in patients whose blood pressure is not adequately controlled with monotherapy.

Brand names

DutoprolLopressor HCT

Other names

metoprolol/hydrochlorothiazidemetoprolol succinate and hydrochlorothiazide